T-Loop Phosphorylation of Arabidopsis CDKA;1 Is Required for Its Function and Can Be Partially Substituted by an Aspartate Residue W OA
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چکیده
Nico Dissmeyer,a Moritz K. Nowack,a,1 Stefan Pusch,a,1 Hilde Stals,b,1 Dirk Inzé,b Paul E. Grini,c and Arp Schnittgera,2 a University of Cologne, University Group at the Max Planck Institute for Plant Breeding Research, Max Delbrück Laboratory, Department of Botany III, 50829 Cologne, Germany b Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology, Ghent University, B-9052 Gent, Belgium c University of Oslo, Department of Molecular Biosciences, N-0316 Oslo, Norway
منابع مشابه
T-loop phosphorylation of Arabidopsis CDKA;1 is required for its function and can be partially substituted by an aspartate residue.
As in other eukaryotes, progression through the cell cycle in plants is governed by cyclin-dependent kinases. Phosphorylation of a canonical Thr residue in the T-loop of the kinases is required for high enzyme activity in animals and yeast. We show that the Arabidopsis thaliana Cdc2(+)/Cdc28 homolog CDKA;1 is also phosphorylated in the T-loop and that phosphorylation at the conserved Thr-161 re...
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تاریخ انتشار 2007